Sweating, fever, and sometimes bloody stools may occur together with diarrhea. Diarrhea may develop and may be severe with colic.

Gastrointestinal tract: About 90% of all patients have abdominal pain or cramps with or without nausea and vomiting.

All patients with cerebral cysticercosis are strongly recommended to be hospitalized during treatment. These side effects may be life-threatening and can be reduced by coadministration of corticosteroids. Almost all patients with cerebral cysticercosis experience CNS side effects related to the cell-death of the parasites (headache, worsening of pre-existing neurological problems, seizures, arachnoiditis, and meningism). Drowsiness, somnolence, fatigue, and vertigo have also been seen.

Central nervous system (CNS): Frequently occurring side effects are dizziness, headache, and malaise.

The heavier the parasite burden, the heavier and more frequent the side effects normally are. The majority of side effects develop due to the release of the contents of the parasites as they are killed and the consequent host immune reaction.

Fasciolopsiasis caused by intestinal fluke Fasciolopsis buski.

Paragonimiasis caused by infection with lung flukes, mostly of the species Paragonimus westermani.

Clonorchiasis brought on by the Chinese liver fluke Clonorchis sinensis.

Schistosomiasis caused by trematodes of the genus Schistosoma: As of 2005, praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose.

Praziquantel is also effective against Echinococcus multilocularis.

In dogs and cats, whose gastrointestinal tracts are infected with the tapeworms Dipylidium caninum or Taenia taeniaeformis, respectively praziquantel is also often used in fixed combination with pyrantel embonate against the roundworms ( ascarids): Toxocara cati and Toxascaris leonina.

Cysticercosis caused by infection of the brain and/or muscles with the eggs and larvae of the pork tapeworm Taenia solium (though it has been judged less effective than albendazole in treatment of neurocysticercosis).

Hydatid disease caused by infection of various organs with larval stages of tapeworms of the genus Echinococcus.Praziquantel is used to treat diseases caused by infection with several types of internal/gastrointestinal, and external parasites, including: It is on the World Health Organization's List of Essential Medicines. Praziquantel was approved for medical use in the United States in 1982. It works partly by affecting the function of the worm's sucker.

Praziquantel is in the anthelmintic class of medications. While it may be used during pregnancy, it is not recommended for use during breastfeeding. Side effects in humans may include poor coordination, abdominal pain, vomiting, headache, and allergic reactions. It should not be used for worm infections of the eye. In humans specifically, it is used to treat schistosomiasis, clonorchiasis, opisthorchiasis, tapeworm infections, cysticercosis, echinococcosis, paragonimiasis, fasciolopsiasis, and fasciolosis. Praziquantel (PZQ), sold under the brandname Biltricide among others, is a medication used to treat a number of types of parasitic worm infections in mammals, birds, amphibians, reptiles, and fish.

Tape worm tab